Displaying 151 - 200 of 316

Genomic Research Through an Indigenous Lens: Understanding the Expectations

Articles » Scholarly, peer reviewed
Author/Creator
Nanibaa’ A. Garrison
Māui Hudson
Leah L. Ballantyne
Ibrahim Garba
Andrew Martinez ... [et al.]
Annual Review of Genomics and Human Genetics, vol. 20, no. 1, 2019, pp. 495-517
Description
Article provides a comparative analysis of guidelines from Canada, New Zealand, Australia, and the United States for research involving Indigenous peoples. Identifies areas that need attention, support Indigenous-led governance, and advocates for research policy framework for genomic research and health care that has international relevance for Indigenous peoples.
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Glossary of Key Terms Related to Intellectual Property and Genetic Resources, Traditional Knowledge and Traditional Cultural Expressions

Alternate Title
Intergovernmental Committee on Intellectual Property and Genetic Resources, Traditional Knowledge and Folkore ; 22nd Session, July 9 to 13, 2012
Documents & Presentations
Author/Creator
[Secretariat of the World Intellectual Property Organization?]
Description
Consolidation of three previous documents: Glossary of Key Terms Related to Intellectual Property and Traditional Cultural Expressions, Glossary of Key Terms Related to Intellectual Property and Traditional Knowledge, and Glossary of Key Terms Related to Intellectual Property and Genetic Resources.
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Glossary of Key Terms Related to Intellectual Property and Genetic Resources, Traditional Knowledge and Traditional Culture

Documents & Presentations
Author/Creator
Intergovernmental Committee on Intellectual Property and Genetic Resources, Traditional Knowledge and Folklore
Description

Terms and definitions drawn from national and regional laws, multilateral instruments, other organizations and processes, and World Intellectual Property Organization (WIPO) documents.

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Hepatitis C Virus Infection Among First Nation and Non-First Nation People in Manitoba, Canada - A Public Health Laboratory Study

Articles » Scholarly, peer reviewed
Author/Creator
Magdy Dawood
Gerry Smart
Michelyn Wood
Hong-Xing Wu
Shirley Paton
Jun Wu
Canadian Journal of Microbiology, vol. 52, October 2006, pp. 999-1005
Description
Explains that even though there was a fourfold increase in the number of specimens tested for anti-hepatitis C virus between 1995 and 2003 there was a decrease in newly identified cases.
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High Prevalence of Lactase Non-Persistence Among Indigenous Nomadic Nenets, North-West Russia

Articles » Scholarly, peer reviewed
Author/Creator
Yulia Khabarova
Valentina Grigoryeva
Sari Tuomisto
Pekka J. Karhunen
Kari Mattila
Mauri Isokoski
International Journal of Circumpolar Health, vol. 71, 2012, p. article no. 17898
Description
Findings indicate individuals with four Nenet grandparents had a 90% probability of having adult-type hypolactsia while those with only one Nenet grandparent had only a 28% chance.
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HLA Class II Alleles in Amerindian Populations: Implications for the Evolution of HLA Polymorphism and the Colonization of the Americas

Articles » Scholarly, peer reviewed
Author/Creator
H.A. Erlich
S.J. Mack
T. Bergstöm
U.B. Gyllensten
Hereditas, vol. 127, no. 1-2, 1997, pp. 19-24
Description
Genetic analysis suggests that modern Amerindian populations are derived from a common ancestral population which likely displayed a similar degree and pattern of DRBl diversity as a result of a founder effect.
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HNF-1α G319S, A Transactivation-Deficient Mutant, is Associated with Altered Dynamics of Diabetes Onset in an Oji-Cree Community

Articles » Scholarly, peer reviewed
Author/Creator
Barbara L. Triggs-Raine
Robert D. Kirkpatrick
Sherrie L. Kelly
Lisa D. Norquay
Peter A. Cattini ... et al.
Proceedings of the National Academy of Sciences of the United States of Amer, vol. 99, no. 7, April 2, 2002, pp. 4614-4619
Description
Discussion of mutations that affect the onset of type 2 diabetes.
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Hopi Indians, Inbreeding, and Albinism

Articles » Scholarly, peer reviewed
Author/Creator
Charles M. Woolf
Frank C. Dukepoo
Science, vol. 164, no. 3875, New Series, April 4, 1969, pp. 30-37
Description
Population genetics: an early study of albinism and its high frequency among the Hopi Indians.
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HPV Genotypes Detected in Cervical Cancers from Alaska Women, 1980-2007

Alternate Title
Proceedings of the 15th International Congress on Circumpolar Health
Articles » Scholarly, peer reviewed
Author/Creator
Janet J. Kelly
Elizabeth R. Unger
Eileen F. Dunne
Neil Murphy
James Tiesinga
Kathy R. Koller Amy Swango-Wilson
Dina Philemonof
Xay Lounmala
Lauri E. Markowitz
Martin Steinau
Thomas Hennessy
International Journal of Circumpolar Health, vol. 72, Supplement 1, 2013, p. article no. 21115
Description
Results found almost two-thirds of the cervical cancers had detectable HPV (human papillomavirus) types 16 or 18.
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Human Genetic Diversity (Immunoglobulin GM Allotypes), Linguistic Data, and Migrations of Amerindian Tribes

Articles » Scholarly, peer reviewed
Author/Creator
Jean-Michel Dugoujon
Bruno Mourrieras
Marie-Therese Senegas
Evelyne Guitard
Andre Sevin
Etienne Bois
Serge Hazout
Human Biology, vol. 67, no. 2, April 1995, pp. 231-250
Description
GM haplotype frequencies used to determine geographic migrations. Geographic and language played an important part in genetic diversity.
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Huntington's Disease

Articles » General
Author/Creator
Marjory Angas
Aboriginal & Islander Health Worker Journal, vol. 5, no. 1, March 1981, pp. 16-19
Description
Explains the symptoms and causes of the disease and how the extended Australian Aboriginal family unit is better equipped to support suffers of the disease.
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Huntington's Disease and Aborigines

Articles » General
Author/Creator
Mark Koolmatrie
Aboriginal and Islander Health Worker Journal, vol. 11, no. 1, March 1987, pp. 39-40
Description
History of the Huntington gene being introduced to Australia.
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Identical Mutation in Patients With Limb Girdle Muscular Dystrophy Type 2B or Miyoshi Myopathy Suggests a Role For Modifer Gene(s)

Articles » Scholarly, peer reviewed
Author/Creator
T. Weiler
R. Bashir
L.V. Anderson
K. Davison
J.A. Moss
S. Britton ... [et al.]
Human Molecular Genetics, vol. 8, no. 5, May 1999, pp. 871-877
Description
Findings emphasize the role for the dysferlin gene as being responsible for both Limb Girdle Muscular Dystroply (LGMD2B) and Miyoshi Myopathy (MM).
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Immunogenetic Risks of Anti-Cyclical Citrullinated Peptide Antibodies in a North American Native Population With Rheumatoid Arthritis and Their First-Degree Relatives

Articles » Scholarly, peer reviewed
Author/Creator
Hani S. El-Gabalawy
David B. Robinson
Donna Hart
Brenda Elias
Janet Markland ... [et al.]
The Journal of Rheumatology, vol. 36, no. 6, June 2009, pp. 1130-1135
Description
Study confirms an association of DRB1*0901 genotypes with Rheumatoid Arthritis (RA).
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Immunogenicity for 16 Serotypes of a Unique Schedule of Pneumococcal Vaccines in a High-Risk Population

Articles » Scholarly, peer reviewed
Author/Creator
Amanda J. Leach
Peter S. Morris
Grant Mackenzie
Joseph McDonnell
Anne Balloch
et al.
Vaccine, vol. 26, 2008, pp. 3885-3891
Description
Schedule of 7-valent pneumococcal conjugate vaccine (7PCV) and 23-valent pneumococcal polysaccharide vaccine (23PPV) for Australian Aboriginal infants in 2001 and found that this population will produce an immunce reponse to 7PCV and 23PPV.
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Immunoglobulin Levels in White and Metis Communities in Saskatchewan

Articles » Scholarly, peer reviewed
Author/Creator
J. W. Gerrand
C. G. Ko
R. Dalgleish
L. K. Tan
Clinical Experimental Immunology, vol. 29, no. 3, 1977, pp. 447-456
Description
Examines serum-immunoglobulin levels and found that they were higher in Métis (Cree) communities than the general population.
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Immunological Parameters and Gene Polymorphisms C-590T IL4, C-597A IL10) in Severe Bronchial Asthma in Children from the Krasnoyarsk Region, West Siberia

Alternate Title
Proceedings of the 15th International Congress on Circumpolar Health
Articles » Scholarly, peer reviewed
Author/Creator
Marina V. Smolnikova
Svetlana V. Smirnova
Maxim B. Freidin
Olga S. Tyutina
International Journal of Circumpolar Health, vol. 72, Supplement 1, 2013, p. article no. 21159
Description
Findings from a study of 100 children revealed that children with uncontrolled brochial asthma have higher CD cell counts.
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Impact of Aboriginal Ethnicity on HCV Core-Induced IL-10 Synthesis: Interaction With IL-10 Gene Polymorphisms

Articles » Scholarly, peer reviewed
Author/Creator
Koko Bate Aborsangaya
Iga Dembinski
Suresh Khatkar
Martin Prince Alphonse
Peter Nickerson
Julia D. Rempel
Hepatology, vol. 45, no. 3, March 2007, pp. 623-630
Description
Although findings suggest First Nations people produce less IL-10, which appears to be beneficial in hepatitis infection, it could negatively impact other disease outcomes.
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Indi-gene-ous Conflicts

Articles » Scholarly, peer reviewed
Author/Creator
Charles W. Schmidt
Environmental Health Perspectives, vol. 109, no. 5, May 2001, pp. A216-A219
Description
Discusses blood samples ostensibly taken from the Nuu-chah nulth tribe for arthritis research, later used for other purposes without subjects' consent.
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Indigenous Peoples and Racism Conference

Articles » General
Author/Creator
Rose Ellis
Aboriginal and Islander Health Worker Journal, vol. 25, no. 2, March/April 2001, pp. 7-12
Description
Provides summaries of the conference speaker's presentations held in Sydney, Australia. One speaker stated that between 99.8% and 99.9% of the human genome is identical, therefore we are much more alike than different.
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Indigenous/Traditional Knowledge & Intellectual Property Law

Alternate Title
Issues Paper (Center for the Study of the Public Domain)
Documents & Presentations
Author/Creator
Jane Anderson
Description
Introductory discussion of the issue, politics and definitional problems, and who is involved, followed by examples of use and misuse of knowledge and cultural expressions, the potential problems and benefits of current proposals, and future directions.
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Intellectual Property and the Ethical/Legal Status of Human DNA: The (Ir)Relevance of Context

Articles » Scholarly, peer reviewed
Author/Creator
Daryl Pullman
George P. Nicholas
Études Inuit Studies, vol. 35, no. 1, Propiété Intellectuelle et Éthique / Intellectual Property and Ethics, 2011, pp. 143-164
Description
Authors feel that relationships themselves between researchers and community members should take precedence over the status of DNA itself.
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Intellectual Property Rights and Indigenous Peoples: Annotated Bibliography

Documents & Presentations
Author/Creator
Jessica Scott Jerome
Description
Divided into seven sections: Legal Frameworks and Analysis; DNA and Property Rights; Historical and Theoretical Accounts of Intellectual Property Rights; Case Studies; Biological Resources and Ethnomedicine; Websites on Intellectual Property Rights and Related Issues; and Organizations.
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Isolation of Candida Dubliniensis in a Aboriginal Community in Ontario, Canada

Articles » Scholarly, peer reviewed
Author/Creator
Laura Montour
Rovena Tey
Jianping Xu
Journal of Clinical Microbiology, vol. 41, no. 7, July 2003, pp. 3423-3426
Description
Study conducted on the Six Nations and New Credit reserves. Results suggest that yeast populations from Indigenous communities in North America may be unique and relatively rare.
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A KCNQ1 V205M Missense Mutation Causes a High Rate Of Long QT Syndrome in a First Nations Community of Northern British Columbia: A Community-Based Approach To Understanding the Impact

Articles » Scholarly, peer reviewed
Author/Creator
Laura Arbour
Saman Rezazdeh
Jodene Eldstrom
Gwen Weget-Simms
Rosemarie Rupps
et al.
Genetics In Medicine, vol. 10, no. 7, July 2008, pp. 545-550
Description
Study identified a missense mutation in two index cases from a northern British Columbia Gitxsan First Nation community which likely increases susceptibility to arrhythmias. Twenty relatives were found to carry the same mutation, while 102 relatives were without the mutation. The identification of this mutation allows diagnosis of a predisposition to the syndrome and medical management.
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