A KCNQ1 V205M Missense Mutation Causes a High Rate Of Long QT Syndrome in a First Nations Community of Northern British Columbia: A Community-Based Approach To Understanding the Impact

Study identified a missense mutation in two index cases from a northern British Columbia Gitxsan First Nation community which likely increases susceptibility to arrhythmias. Twenty relatives were found to carry the same mutation, while 102 relatives were without the mutation. The identification of this mutation allows diagnosis of a predisposition to the syndrome and medical management.
Author/Creator
Laura Arbour
Saman Rezazdeh
Jodene Eldstrom
Gwen Weget-Simms
Rosemarie Rupps
et al.
Open Access
No
Primary Source
No
Citation
Genetics In Medicine, vol. 10, no. 7, July 2008, pp. 545-550
Publication Date
2008-07
Location
Resource Type
Articles -- Scholarly, peer reviewed
Format
Text -- PDF
Text -- HTML
Language
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