A Single Nucleotide Polymorphism in Protein Tyrosine Phosphatase PTP-1B Is Associated with Protection from Diabetes or Impaired Glucose Tolerance in Oji-Cree
Articles » Scholarly, peer reviewed
Author/Creator
Andrea Mok
Henian Cao
Bernard Zinman
Anthony J. G. Hanley
Stewart B. Harris
Brian P. Kennedy
Robert A. Hegele
Journal of Clinical Endocrinology & Metabolism, vol. 87, no. 2, February 2002, pp. 724-727
Description
Report on the development of reagents for the amplification and sequencing PTP-1B gene and the resulting identification of a single nucleotide polymorphism. It is noted that these very preliminary results suggest genomic variation in PTP-1B is linked with less risk of developing diabetes.