A Single Nucleotide Polymorphism in Protein Tyrosine Phosphatase PTP-1B Is Associated with Protection from Diabetes or Impaired Glucose Tolerance in Oji-Cree

Report on the development of reagents for the amplification and sequencing PTP-1B gene and the resulting identification of a single nucleotide polymorphism. It is noted that these very preliminary results suggest genomic variation in PTP-1B is linked with less risk of developing diabetes.
Author/Creator
Andrea Mok
Henian Cao
Bernard Zinman
Anthony J. G. Hanley
Stewart B. Harris
Brian P. Kennedy
Robert A. Hegele
Open Access
No
Primary Source
No
Citation
Journal of Clinical Endocrinology & Metabolism, vol. 87, no. 2, February 2002, pp. 724-727
Publication Date
2002-02
Location
Resource Type
Articles -- Scholarly, peer reviewed
Format
Text -- PDF
Text -- HTML
Language
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