Genetics

Study indicates an absence of a specific gene contributes to albinism.

Study found that while the presence of the AGT -6A variant tended to be associated with higher systolic blood pressure, it was not found to be significant in this population of Canadian Oji-Cree.

Findings of testing on 3 distinct populations, Hutterites, Oji-Cree and Keewatin Inuit, indicate there's no consistent relationship between the population mean plasma HDL cholesterol concentration and then population LIPC-480T frequency.

Study undertaken to determine if there is a relationship between ADRB3 R64 allele and obesity and type 2 diabetes in a sample of Aboriginal Canadians.

Investigation of possible genetic determinants for type 2 diabetes.

Research agreements must be structured to ensure mutual benefits which reflect the equal status of both parties.

Conclusions indicated that AP in the Inuit is a seasonal photodermatitis which often commences in adulthood and worsens over time. Study found a novel HLA association.

Reports on Aboriginal activists lobbing to restrict genetic research on Indigenous cell lines as part of the International Human Genome Diversity Project in Winnipeg, Manitoba.

Discusses admixture mapping, a method which is used to identify genetic risk factors in complex diseases such as Type 2 diabetes between major continental groups.

Reports how the Alaska Area Specimen Bank (AASB) is a valuable resource and can be used to assess early markers for illness and disease.

Studies gene found in high-frequency in the Naskapi people of Quebec.

Studies relationship of genetic consistency between the Naskapi of Quebec and the Eti Turks of Turkey

Pharmacology Thesis (Ph.D.)--University of Toronto, 2003.

Sections include: frequently asked questions, summary tools, basics of genetics, decisions about research, case studies, regulating research, and use of DNA for purposes of determining tribal enrollment.

Discusses the media's framing of the Havasupai case against the Arizona State University's genomic research as a matter of ethics rather than an issue of Indigenous sovereignty.

Looks at new research, in the fields of anthropology and molecular genetics, to study biological affiliation and historic population movements.

Findings provide the first characterization of the human pyruvate carboxylase gene structure, identify common pathogenic mutations, as well as demonstrate founder effect in the study's Ojibwa and Cree patients.

Genetic testing results suggest that Amerindian and Na-Dene populations have separate origins and are compatible with previous studies indicating the two populations are derived from different migrations from Asia.

DNA study that supports the theory that the founding Eskimo/Aleut peoples originated in Alaska.

Highlights the continuity between extractive colonial practices such as land dispossession and biocolonial activities regarding the mining of the human body.

Anthropology Thesis (Ph.D.)--University of California, Davis, 2005.

Discusses the classical stringent standards to retrieve and authenticate DNA from ancient remains and puts forth recommendations for future discoveries and progression of the ancient DNA field.

Discussion of how new techniques allow genetics of extinct populations to be studied but raise ethical questions about using museum collections to gather samples.

Anthropology Thesis (M.A.)--University of Manitoba, 2013.

Anthropology Thesis (M.A.)--University of Kansas, 2007.

Examines research literature and finds that biochemical studies do not support this theory; cautions against simplistic approach to a complex issue.

Discussion of the higher risk for obesity, the need for ethnospecific obesity criteria and health interventions.

Investigates the degree to which Sámi DNA is carried by the non-Sámi populations of the Scandinavian countries.

Study results of Canadians of South Asian and Chinese descent, Oji-Cree and Inuit (Greenland) indicated that the association between FTO gene associated with obesity extends to non-Caucasian subjects.

Medical Microbiology and Infectious Diseases Thesis (M.Sc.)--University of Manitoba, 2013.

Using family material from the Naskapi and Montagnais Indians of the Labrador peninsula, the authors found evidence for close linkage between the loci that determine the two inherited traits.

Bibliography is divided into five categories: Social and cross cultural aspects of health and disease, Health, health education, and health care delivery, Genetics and metabolism, Infectious diseases, and Noninfectious/Chronic health problems.

Looks at the success or failure of laws and policies that were meant to protect community rights, culture, and material resources and the use of community protocols as tools.

Looks at bioethical aspects of prenatal DNA diagnosis of hereditary diseases.

Examines the differences found in Iroquois and Algonquians to determine the genetic drift between them.

Findings indicate relatively diverse backgrounds with little gene flow between the two groups, each presumably having arisen from relatively distant common ancestry.

Book review of: Biomapping Indigenous Peoples edited by Susanne Berthier-Foglar, Sheila Collingwood-Whittick, and Sandrine Tolazzi. Review located by scrolling to page 139.

Brief description of one day workshop, An Introduction to Medical Genetics attended by Aboriginal health officers.

Discussion of the public and media fascination with history, identity and heredity.

Discusses blood types and genetic factors of Shubenacadie children in Nova Scotia.

Findings indicate that the two groups appear to have significantly different gene pools with respect to some blood groups which would consider them distinct sub-populations.

Exposes an incident where 200 people gave blood to aid research into their diabetes epidemic; the samples were also used to do research into Havasupai genes and schizophrenia, inbreeding, and the Bering Strait theory without their consent. The Havasupai people filed a lawsuit against the Arizona State University for intentional deception.

Discusses 25 lithic artifacts from 2 sites that test positive for sturgeon, deer, rabbit, bear, cat, mouse and human blood.

Report examines treatment on 18 Navajo and Dene children with SCIDA. Findings demonstrate the efficacy of bone marrow transplantation when treating infants with this distinct form of SCID and indicates those who were treated with immunosuppressive and myeloablative therapy had a poor outcome.

Author presents a challenge to what she perceives will be the future of genetic engineering.

Study, which reports on two families with the same BRCA1 mutation, finds the first evidence of a BRCA1 mutation that is specific to North American aboriginal people.

Results revealed the remains share an mtDNA type with North American, Central American and South American populations.

Study findings indicate that Canadian Aboriginal subjects differ from both Asian and Caucasian genotype patterns for these mutant alleles, which may have consequences for clinical drug use among Canadian Aboriginals.

Biochemistry and Medical Genetic Thesis (M.Sc.)--University of Manitoba, 2005.

Properties of ear wax (cerumen) of 483 Native Americans has frequency close to mongoloid peoples and origins.