Sandy Lake

Investigation into adiponectin, leptin, C-reactive protein, interleukin 6, and serum amyloid A, individually or in combinations, and finding that low baseline adiponectin is associated with increased risk of incident type 2 diabetes independent of leptin, C-reactive protein, interleukin 6, serum amyloid A, and obesity.

Focuses on the protein adiponectin and its relation to obesity, type 2 diabetes and cardiovascular disease.

Community Health Thesis (M.Sc.)--University of Toronto, 2001.

Assessment of 236 youths age 10 to 19 in the Oji-Cree community of Sandy Lake, Ontario.

Study to determine the performance characteristics of HNFIA for impaired glucose tolerance in Oji-Cree.

Research project using validated methods to determine the prevalence of renal complications with diabetes.

Study done between 1993 and 1995 with people from Sandy Lake in northern Ontario.

Corrections to article on study done between 1993 and 1995 with people from Sandy Lake in northern Ontario. Second Erratum.

Investigates a genetic variant to explain the low prevalence of cardiovascular disease in this sample population.

Studies the ß-cell response to elevation of plasma free fatty acids and to compare this response to that of nondiabetic Caucasian subjects.

Identification of a new genetic mutation which results in the substitution of serine for glycine.

Indian and Northern Education Thesis (M.Ed.)--University of Saskatchewan, 1989.

Looks at the incidence of type 2 diabetes in the Sandy Lake First Nation (Ontario) and evaluates prospective associations with metabolic syndrome and its components.

Study findings showed physical activity and fitness had a beneficial effect on insulin sensitivity.

File contains a presentation by Bob Rosehart focusing on Lakehead University programs that are directed toward Aboriginal students, including language, teacher, nursing, engineering and culture classes. Lakehead University also has a student support system and drop-in centre for Aboriginal students. Following the presentation is a question-and-answer session with the Commissioners.

Report on the development of reagents for the amplification and sequencing PTP-1B gene and the resulting identification of a single nucleotide polymorphism. It is noted that these very preliminary results suggest genomic variation in PTP-1B is linked with less risk of developing diabetes.

Discusses study undertaken to evaluate the relationship between the genetic marker and the disease.